Recent studies have demonstrated that low molecular weight fluorescence probes (LMFPs) based on coumarin-enamine can effectively phosphorylate nerve agent mimics such as diisopropyl fluorophosphate (DFP), diisopropyl chlorophosphate (DCP), and diethylcyanophosphonate (DECP). This discovery highlights the potential of LMFPs as an essential tool for detecting these harmful substances. A new coumarin-enamine chemo-dosimeter, featuring diverse functional groups on the nitrogen atom at position 7 of the coumarin backbone, has been introduced. When combined with a luminophore (Ru(bpy)32+), the tertiary amine serves as a co-reactant in electrogenerated chemiluminescence (ECL).
