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Nazmul Hosen

Ph.D. Candidate

Chemistry and Biochemistry

University of Southern Mississippi

Nazmul Hosen

Ph.D. Candidate

Chemistry and Biochemistry

University of Southern Mississippi

Synthesis and photophysical properties of coumarin-quinoline derivatives for sensor development

  • First author: Nazmul Hosen
  • Co-author: Leah Case
  • Corresponding author: Karl J. Wallace

Overview
I design small-molecule fluorophores for sensing. I built a compact library of coumarin–quinoline (CQ) and coumarin–imine (CI) scaffolds in three steps and fully characterized each compound.

Highlights

  • Reaction conditions control selectivity: higher temperature and longer time favor CQ; lower temperature and shorter time favor CI.

  • I mapped absorption and emission in acetonitrile to study solvatochromism and brightness, building structure–property rules for sensor design.

My role
Synthesis, purification, full characterization, and steady-state photophysics.

Status
Dataset expanded; manuscript in preparation.